Kamis, 19 September 2019

Combinatorial materials science: Paradigm shift in materials discovery and optimization

          The ability to generate not just a single material with improved properties, but multiple materials (of different structure and/or composition) with these properties would, no doubt, increase the probability that at least one of these candidates could be integrated successfully into a commercial technology. Combinatorial chemistry the technique of creating vast numbers of compounds by reacting a set of components in all possible combinations at once has been adopted nearly universally by the pharmaceutical industry in their search for new drugs.

             Synthetic strategies in these industries, unlike pharmaceuticals, vary from thin film methods such as physical and chemical vapor deposition to more traditional bulk techniques and the use electrochemical methods.screening strategies can also vary widely, depending on the targeted application of the material. In another proof of concept study, selim senkan of university of California at los angeles has employed resonant enhanced multiphotonionization to examine the catalytic dehydrogenation of cyclohexane to benzene.

          As a final example illustrating the power of the combinatorial approach, we consider heterogeneous catalysts for the oxidative dehydrogenation of ethane to ethylene. On the order of 20 ago. Youang and coworkers at union carbide investigatied this reaction over mixed metal oxides and found that those composed of Mo, V and Nb provided superior performance, particularly at low temperatures.

source : proquest

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